3-[3-(trifluoromethoxy)phenyl]prop-2-enoate

3-[3-(trifluoromethoxy)phenyl]prop-2-enoate - Names and Identifiers

Name	3-(Trifluoromethoxy)cinnamic acid
Synonyms	RARECHEM BK HW 0216 3-(Trifluoromethoxy)cinnamic acid 3-(TRIFLUOROMETHOXY)CINNAMIC ACID TRANS-3-(TRIFLUOROMETHOXY)CINNAMIC ACID 3-[3-(trifluoromethoxy)phenyl]prop-2-enoate 3-(3-Trifluoromethoxyphenyl)-2-propenoicacid 3-[3-(trifluoromethoxy)phenyl]prop-2-enoic acid
CAS	168833-80-5
EINECS	625-131-6
InChI	InChI=1/C10H7F3O3/c11-10(12,13)16-8-3-1-2-7(6-8)4-5-9(14)15/h1-6H,(H,14,15)/p-1/b5-4+

3-[3-(trifluoromethoxy)phenyl]prop-2-enoate - Physico-chemical Properties

Molecular Formula	C10H7F3O3
Molar Mass	232.16
Density	1.403
Melting Point	92-96 °C (lit.)
Boling Point	286℃
Flash Point	127℃
Vapor Presure	0.0013mmHg at 25°C
pKa	4.27±0.10(Predicted)
Storage Condition	Room Temprature
MDL	MFCD00066337
Physical and Chemical Properties

3-[3-(trifluoromethoxy)phenyl]prop-2-enoate - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26/37/39 -
UN IDs	UN 2811 6.1/PG 3
WGK Germany	3
HS Code	29189900
Hazard Class	IRRITANT

3-[3-(trifluoromethoxy)phenyl]prop-2-enoate - Introduction

3-(Trifluoromethoxy)cinnamic acid is an organic compound with the chemical formula C10H9F3O3. The following is a description of its nature, use, formulation and safety information:

1. Nature:
3-(Trifluoromethoxy)cinnamic acid is a white solid with a strong aromatic odor. It is soluble in some organic solvents, such as methanol and dichloromethane, and insoluble in water. The compounds have antibacterial, antioxidant and anti-inflammatory activities.

2. Use:
3-(Trifluoromethoxy)cinnamic acid is a commonly used organic synthesis intermediate. It can be used to synthesize other compounds, such as drugs, fragrances and dyes. In addition, due to its antibacterial and antioxidant properties, it is also used in skin care products and medicine.

3. Preparation method:
3-(Trifluoromethoxy)cinnamic acid can be synthesized by various ways. The common method is to react cinnamic acid with trifluoromethanol. Specific operation can refer to the relevant literature of organic synthetic chemistry.

4. Safety Information:
3-(Trifluoromethoxy)cinnamic acid has low toxicity, but it is still necessary to pay attention to safe operation. The dust is irritating to the eyes and skin and may cause allergic reactions. During operation, wear suitable personal protective equipment to avoid inhalation or contact with the compound. At the same time, it should be stored in a dry, cool place, and away from fire and oxidizing agents. In case of accidental splashing, appropriate cleaning methods shall be taken to avoid environmental pollution and personal harm.

Last Update：2024-04-09 21:11:58